The GIFT process begins the same way as a regular IVF cycle. First, your ovaries are stimulated using a series of hormone injections, to encourage egg development and maturation. You will then be given an injection to trigger ovulation, and the eggs contained within the follicles are collected in a day surgery procedure. Show
With GIFT, instead of the eggs being then placed together in a dish with your partner's sperm, the best-looking egg is transferred into your fallopian tubes along with your partner’s sperm, using a laparoscope. OverviewIn vitro fertilization (IVF) is a complex series of procedures used to help with fertility or prevent genetic problems and assist with the conception of a child. During IVF, mature eggs are collected (retrieved) from ovaries and fertilized by sperm in a lab. Then the fertilized egg (embryo) or eggs (embryos) are transferred to a uterus. One full cycle of IVF takes about three weeks. Sometimes these steps are split into different parts and the process can take longer. IVF is the most effective form of assisted reproductive technology. The procedure can be done using a couple's own eggs and sperm. Or IVF may involve eggs, sperm or embryos from a known or anonymous donor. In some cases, a gestational carrier — someone who has an embryo implanted in the uterus — might be used. Your chances of having a healthy baby using IVF depend on many factors, such as your age and the cause of infertility. In addition, IVF can be time-consuming, expensive and invasive. If more than one embryo is transferred to the uterus, IVF can result in a pregnancy with more than one fetus (multiple pregnancy). Your doctor can help you understand how IVF works, the potential risks and whether this method of treating infertility is right for you. Products & Services
Why it's doneIn vitro fertilization (IVF) is a treatment for infertility or genetic problems. If IVF is performed to treat infertility, you and your partner might be able to try less-invasive treatment options before attempting IVF, including fertility drugs to increase production of eggs or intrauterine insemination — a procedure in which sperm are placed directly in the uterus near the time of ovulation. Sometimes, IVF is offered as a primary treatment for infertility in women over age 40. IVF can also be done if you have certain health conditions. For example, IVF may be an option if you or your partner has:
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You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. RisksRisks of IVF include:
How you prepareThe Centers for Disease Control and Prevention and the Society for Assisted Reproductive Technology provide information online about U.S. clinics' individual pregnancy and live birth rates. A clinic's success rate depends on many factors. These include patients' ages and medical issues, as well as the clinic's treatment population and treatment approaches. Ask for detailed information about the costs associated with each step of the procedure. Before beginning a cycle of IVF using your own eggs and sperm, you and your partner will likely need various screenings, including:
Before beginning a cycle of IVF, consider important questions, including:
What you can expectIVF involves several steps — ovarian stimulation, egg retrieval, sperm retrieval, fertilization and embryo transfer. One cycle of IVF can take about two to three weeks. More than one cycle may be needed. Ovulation inductionThe start of an IVF cycle begins by using synthetic hormones to stimulate the ovaries to produce multiple eggs — rather than the single egg that typically develops each month. Multiple eggs are needed because some eggs won't fertilize or develop normally after fertilization. Several different medications may be used, such as:
Your doctor will work with you to determine which medications to use and when to use them. Typically, you'll need one to two weeks of ovarian stimulation before your eggs are ready for retrieval. To determine when the eggs are ready for collection, you may have:
Sometimes IVF cycles need to be canceled before egg retrieval for one of these reasons:
If your cycle is canceled, your doctor might recommend changing medications or their doses to promote a better response during future IVF cycles. Or you may be advised that you need an egg donor. Egg retrievalEgg retrieval can be done in your doctor's office or a clinic 34 to 36 hours after the final injection and before ovulation.
Sperm retrievalIf you're using your partner's sperm, a semen sample needs to be provided at your doctor's office or clinic the morning of egg retrieval. Typically, the semen sample is collected through masturbation. Other methods, such as testicular aspiration — the use of a needle or surgical procedure to extract sperm directly from the testicle — are sometimes required. Donor sperm also can be used. Sperm are separated from the semen fluid in the lab. FertilizationFertilization can be attempted using two common methods:
In certain situations, your doctor may recommend other procedures before embryo transfer.
Embryo transferEmbryo transfer is done at your doctor's office or a clinic and usually takes place two to five days after egg retrieval.
If successful, an embryo will implant in the lining of your uterus about six to 10 days after egg retrieval. After the procedureAfter the embryo transfer, you can resume your usual daily activities. However, your ovaries may still be enlarged. Consider avoiding vigorous activity, which could cause discomfort. Typical side effects include:
If you develop moderate or severe pain after the embryo transfer, contact your doctor. He or she will evaluate you for complications such as infection, twisting of an ovary (ovarian torsion) and severe ovarian hyperstimulation syndrome. ResultsAbout 12 days to two weeks after egg retrieval, your doctor will test a sample of your blood to detect whether you're pregnant.
The chances of giving birth to a healthy baby after using IVF depend on various factors, including:
Talk with your doctor about any factors that apply to you and how they may affect your chances of a successful pregnancy. Clinical trialsExplore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions. Sept. 10, 2021 WHAT IS GIFT and ZIFT procedure?The processes used in GIFT and ZIFT are closer to natural conception. In ZIFT, the eggs are placed in the fallopian tubes rather than directly in the uterus. With GIFT, fertilization actually takes place in the body rather than in a petri dish. However, in vitro fertilization techniques have become more refined.
What is the process of ZIFT?Zygote intra fallopian transfer (ZIFT) is an infertility treatment used when a blockage in the fallopian tubes prevents the normal binding of sperm to the egg. Egg cells are removed from a woman's ovaries, and in vitro fertilised. The resulting zygote is placed into the fallopian tube by the use of laparoscopy.
What is the procedure that implants a fertilized egg in the fallopian tube?IVF is the most effective form of assisted reproductive technology. The procedure can be done using a couple's own eggs and sperm. Or IVF may involve eggs, sperm or embryos from a known or anonymous donor. In some cases, a gestational carrier — someone who has an embryo implanted in the uterus — might be used.
What do you mean by ZIFT?ZIFT: Stands for zygote intrafallopian transfer, a method used to treat infertility in which an egg fertilized in vitro (outside the body) is placed into a woman's fallopian tube. This technique is one used to overcome infertility, the inability of couples to produce offspring on their own.
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