Emphysema is a lung disease that results from destruction of lung tissue and irreversible enlargement of the alveoli (air sacs) that deliver oxygen to and remove carbon dioxide from the blood. As the walls of the alveoli become progressively enlarged, they lose elasticity and have a reduced ability to force air out of the lungs during expiration. As a result, the affected air sacs cannot properly fill up with fresh air during inspiration,
and the exchange of oxygen and carbon dioxide between the alveoli and the blood becomes impaired. This leads to the shortness of breath that characterizes emphysema. Along with chronic bronchitis, emphysema is one of the primary lung disorders that constitutes chronic obstructive pulmonary disease, or COPD The onset of emphysema is gradual, with symptoms typically developing after age 50; however, irreversible lung damage may occur long before symptoms become severe
enough to warrant medical attention. Such damage is initiated by smoking or other lung irritants, which lead to the destruction of lung tissue. The prognosis for patients who have emphysema varies, depending on the severity of the condition and whether or not the patient continues to smoke. Although the disease is progressive and irreversible, patients who stop smoking and receive oxygen therapy generally have a longer life expectancy. According to the
American Lung Association, more than 3.1 million people in the United States have been diagnosed with emphysema. Emphysema and other types of COPD are the fourth leading cause for death in the United States. The condition occurs slightly more often in men (about 52 percent of cases) than women; however, the mortality rate is higher in women. Emphysema is more common in Caucasians than African Americans. More than 90 percent of patients who have emphysema are over the age of 45 at the time
of diagnosis. The disease is most common between the ages of 60 and 80. Approximately 100,000 people in the United States have an inherited form of the condition called alpha-1 antitrypsin deficiency emphysema or familial emphysema. This disease, which is more common in people of northern European descent, often causes symptoms between the ages of 32 and 40. Shortness of breath. Wheezing. Cough (wet or dry). Fatigue. Weight loss. Barrel-chested appearance. Cyanosis (bluish tint to the lips, fingertips, and skin; caused by low levels of oxygen [O2] in the blood). Edema (swelling; commonly in the feet and ankles). Headaches (especially upon waking in the morning as a result of low oxygen levels during sleep). What If You Do Nothing?If emphysema goes untreated, and especially is a patient continues to smoke, symptoms will worsen. In addition, emphysema can lead to a number of complications that include:
Causes/Risk Factors
DiagnosisTo diagnose emphysema, the doctor takes a complete patient and family medical history and performs a physical examination. If these suggest a diagnosis of emphysema, diagnostic tests may be performed. Tests used to diagnose emphysema include the following:
Emphysema is an irreversible condition and the goals of treatment are to reduce symptoms and to slow progression of the disease. The most important step is to quit smoking. Smoking cessation can slow the decline of lung function considerably. Treatment for emphysema may include the following:
PreventionAvoiding exposure to cigarette smoke is the most effective way to prevent developing emphysema. And while nearly all smokers suffer some lung damage, quitting smoking can prevent further lung deterioration. Maintaining a healthy lifestyle (e.g., exercising regularly, eating properly), avoiding exposure to air pollution and second-hand smoke, and receiving prompt medical treatment for respiratory infections also can help prevent emphysema. When To Call Your DoctorCall a doctor if you experienced worsening of shortness of breath or if symptoms of emphysema become more severe. Reviewed by Allen J. Blaivas, D.O., Division of Pulmonary, Critical Care, and Sleep Medicine, VA New Jersey Health Care System, Clinical Assistant Professor, Rutgers New Jersey Medical School, East Orange, NJ. Review provided by VeriMed Healthcare Network. What walls of alveoli deteriorate and lose their elasticity?Emphysema is a condition that involves damage to the walls of the air sacs (alveoli) of the lung.
What causes alveoli to lose elasticity?When you breathe out, the air sacs deflate, and the air goes out. In emphysema, the walls between many of the air sacs in the lungs are damaged. This causes the air sacs to lose their shape and become floppy.
What causes alveoli disease?Causes of acute alveolar lung disease include pulmonary edema (cardiogenic or neurogenic), pneumonia (bacterial or viral), systemic lupus erythematosus, bleeding in the lungs (e.g., Goodpasture syndrome), idiopathic pulmonary hemosiderosis, and granulomatosis with polyangiitis.
What diseases affect the alveoli?Lung Diseases Affecting the Air Sacs (Alveoli). Pneumonia. ... . Tuberculosis Pneumonia that slowly gets worse, caused by the bacteria Mycobacterium tuberculosis.. Emphysema. ... . Pulmonary edema. ... . Lung cancer. ... . Acute respiratory distress syndrome (ARDS). ... . Pneumoconiosis.. |