Thermoregulation refers to how the body maintains its internal temperature. If your body temperature becomes too cold or hot, it may lead to severe symptoms and even death. Show Thermoregulation is a process that allows your body to maintain its core internal temperature. All thermoregulation mechanisms help return your body to homeostasis. This is a state of equilibrium. A typical internal body temperature falls within a narrow window. The average person has a baseline temperature between 98°F (37°C) and 100°F (37.8°C). Your body has some flexibility with temperature. However, getting to the extremes of body temperature can affect your body’s ability to function. For example, if your body temperature falls lower than 96°F (35°C) or lower, you have hypothermia. This condition can lead to cardiac arrest, brain damage, or even death. You can experience heat stroke if your body temperature rises above 104°F (40°C). Heat stroke is considered a medical emergency. If your body temperature rises to high, you can experience brain damage or even death. Many factors can affect your body’s temperature, such as spending time in cold or hot weather. Factors that can raise your internal temperature include:
Factors that can lower your internal temperature include:
Your hypothalamus is a section of your brain that controls thermoregulation. When the hypothalamus senses your internal temperature becoming too low or high, it sends signals to your muscles, organs, glands, and nervous system. They respond in various ways to help return your temperature to its typical levels. When your internal temperature changes, sensors in your central nervous system send messages to your hypothalamus. In response, it sends signals to various organs and systems in your body. They respond with a variety of mechanisms. If your body needs to cool down, these mechanisms include:
If your body needs to warm up, these mechanisms include:
If your internal temperature drops or rises outside of the typical range, your body will take steps to adjust it. This process is known as thermoregulation. It can help you avoid or recover from potentially dangerous conditions like hypothermia.
Homeostasis is the ability to maintain a relatively stable internal state that persists despite changes in the world outside. All living organisms, from plants to puppies to people, must regulate their internal environment to process energy and ultimately survive. If your blood pressure skyrockets or body temperature plummets, for example, your organ systems may struggle to do their jobs and eventually fail. Why is homeostasis important?Physiologist Walter Cannon coined the term "homeostasis" in the 1920s, expanding on previous work by late physiologist Claude Bernard. In the 1870s, Bernard described how complex organisms must maintain balance in their internal environment, or "milieu intérieur,"in order to lead a "free and independent life"in the world beyond. Cannon honed the concept, and introduced homeostasis to popular audiences through his book, "The Wisdom of the Body"(The British Medical Journal, 1932). Hailed as a core tenet of physiology, Cannon's basic definition of homeostasis remains in use today. The term derives from Greek roots meaning "similar" and "a state of stability." The prefix "homeo" stresses that homeostasis doesn't work like a thermostat or cruise control in a car, fixed at one precise temperature or speed. Instead, homeostasis holds important physiological factors within an acceptable rangeof values, according to a review in the journal Appetite (opens in new tab). Related: Has the average human body temperature always been the same? The human body, for example, regulates its internal concentrations of hydrogen, calcium, potassium and sodium, charged particles that cells rely on for normal function. Homeostatic processes also maintain water, oxygen, pH and blood sugar levels, as well as core body temperature, according to a 2015 review in Advances in Physiology Education (opens in new tab). In healthy organisms, homeostatic processes unfold constantly and automatically, according to Scientific American (opens in new tab). Multiple systems often work in tandem to hold steady a single physiological factor, like body temperature. If these measures falter or fail, an organism may succumb to disease, or even death. How is homeostasis maintained?Many homeostatic systems listen for distress signals from the body to know when key variables fall out of their appropriate range. The nervous system detects these deviations and reports back to a control center, often based in the brain. The control center then directs muscles, organs and glands to correct for the disturbance. The continual loop of disturbance and adjustment is known as "negative feedback," according to the online textbook Anatomy and Physiology (opens in new tab). For example, the human body maintains a core temperature of about 98.6 degrees Fahrenheit (37 degrees Celsius). When overheated, thermosensors in the skin and brain sound an alarm, initiating a chain reaction that directs the body to sweat and flush. When chilled, the body responds by shivering, and reducing blood circulation to the skin. Similarly, when sodium levels spike, the body signals the kidneys to conserve water and expel excess salt in concentrated urine, according to two NIH-funded studies (opens in new tab). Animals will also adjust their behavior in response to negative feedback. For example, when overheated, we may shed a layer of clothing, move into the shade, or drink a cold glass of water. Modern models of homeostasisThe concept of negative feedback dates back to Cannon's description of homeostasis in the 1920s, and was the first explanation of how homeostasis works. But in recent decades, many scientists have argued that organisms are able to anticipate potential disruptions to homeostasis, rather than only reacting to them after the fact. This alternate model of homeostasis, known as allostasis, implies that the ideal set point for a particular variable can shift in response to transient environmental changes, according to a 2015 article in Psychological Review (opens in new tab). The point may shift under the influence of circadian rhythms, menstrual cycles or daily fluctuations in body temperature. Set points may also change in response to physiological phenomena, like fever, or to compensate for multiple homeostatic processes taking place at the same time, according to a 2015 review in Advances in Physiology Education (opens in new tab). "The set points themselves aren't fixed but can show adaptive plasticity," said Art Woods, a biologist at the University of Montana in Missoula. "This model allows for anticipatory responses to upcoming potential disturbances to set points." For example, in anticipation of a meal, the body secretes extra insulin, ghrelin and other hormones, according to a 2007 review in Appetite (opens in new tab). This preemptive measure readies the body for the incoming flood of calories, rather than wrestling to control blood sugar and energy stores in its wake. The ability to shift set points allows animals to adapt to short-term stressors, but they may fail in the face of long-term challenges, such as climate change. "Activating homeostatic response systems can be fine for short periods of time," Woods said. But they're not designed to last for long. "Homeostatic systems can fail catastrophically if they are pushed too far; so, although systems may be able to handle near-term novel climates, they may not be able to handle larger changes over longer periods of time." An "information hypothesis" for homeostasisHomeostatic systems may have primarily evolved to help organisms maintain optimal function in different environments and situations. But, according to a 2013 essay in the journal Trends in Ecology & Evolution (opens in new tab), some scientists theorize that homeostasis primarily provides a "quiet background" for cells, tissues and organs to communicate with each other. The theory posits that homeostasis makes it easier for organisms to extract important information from the environment and shuttle signals between body parts. Regardless of its evolutionary purpose, homeostasis has shaped research in the life sciences for nearly a century. Though mostly discussed in the context of animal physiology, homeostatic processes also enable plants to manage energy stores, nourish cells and respond to environmental challenges. Beyond biology, the social sciences, cybernetics, computer science and engineering all use homeostasis as a framework to understand how people and machines maintain stability despite disruptions. Additional resourcesCheck out helpful graphics about homeostasis from the Khan Academy (opens in new tab). Learn how homeostasis impacts human physiology with Crash Course (opens in new tab). Watch this video from the Amoeba Sisters (opens in new tab) to learn more about negative feedback. Originally published on Live Science. Nicoletta Lanese is a staff writer for Live Science covering health and medicine, along with an assortment of biology, animal, environment and climate stories. She holds degrees in neuroscience and dance from the University of Florida and a graduate certificate in science communication from the University of California, Santa Cruz. Her work has appeared in The Scientist Magazine, Science News, The San Jose Mercury News and Mongabay, among other outlets. |
The stable, constant internal environment that our body maintains at rest is known as
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